The germinal center (GC) is a transient anatomical structure formed through the adaptive immune response leading to antibody affinity maturation and serological memory. through the GC response. FrAImmature B Transitional 1 Dark area/Light zoneApop immPlasma cellIgMSerum Serum Serum Serum Serum Serum IgGserum Serum Serum Serum Serum Serum T-independentTNP-FicollDNP-FicollTNP-FicollTNP-LPSTNP-LPSTNP-FicollPPSV;TNP-LPS; TNP-FicollTNP-FicollTNP-Ficoll/LPSTNP-FicollIgMMZB IgG2bIgG IgG IgG3In vitro anti-BCR responseCell… Continue reading The germinal center (GC) is a transient anatomical structure formed through the adaptive immune response leading to antibody affinity maturation and serological memory